Description Superheated water sterilizers are able to perform counterpressure sterilization of large volume parenteral solutions through a superheated water spray system.

In compliance with cGMP and FDA standards for LVP products, the superheated water sterilizers are suitable for treating loads in containers that may be deformed due to the difference in pressure between the chamber and the container itself.

Where the product is liable to separation or for accelerating thermal transition phases, the whole load can be rotated during the entire sterilization process.

• Sterilization of parenteral solutions, liquids in sealed containers not deformable (eg. glass vials) and liquids in heat sensitive sealed containers (eg. plastic bags or bottles).
• Terminal sterilization of pre-filled syringes (PFSs)

Rotating Load

The load is held in rotation thanks to a special rotating drum inside the chamber. The rotation drum has a magnetic coupling and is adjustable in speed, direction of rotation and intermittently. This system finds application in the treatment of suspensions and emulsions and ensures a better performance of the tightness tests for ampoules under vacuum and a more homogeneous heat transmission in the load.